245 Results were found on Technologies
Sub Category Name
MAPPING THE SITES OF INTERACTION OF THE SMALL GTPASE RAB12 WITH ITS RILP FAMILY EFFECTOR PROTEINS
We have recently shown that the small GTPase Rab12, which was previously shown to control housekeepingfunctions, such as autophagy and iron regulation1,2, negatively regulates degranulation of mastcells (MCs), by binding and recruiting the RILP-dynein motor complex to the MC secretory granules(SGs), and driving their retrograde transport, thus restricting degranulation3. These results havemarked the Rab12-RILP complex […] Read More >
A novel method to remotely detect plant sound emission, as a response to induced stress
A novel system developed to remotely detect plant sound emission, as a response to stress. The system consists of hardware and software components: microphones that remotely pick up the plant’s sounds in the ultrasonic range of 20 to 100 kilohertz; a signal processing layer; and a machine-learning algorithm that classifies the recorded sounds and reports […] Read More >
A Fully Integrated Chip Scale Dielectric Resonance Antenna
Due to limited voltage supplies in scaled CMOS and the lower amplitude of harmonic generation at frequencies above transistors’ fmax, the radiated power out of a single element around 300GHz is limited to 0.5mW. Generating more power by combining signals from several locked sources on chip to the same on-chip antenna is not efficient due […] Read More >
Mirna for the Treatment of Metastatic Breast Cancer
Metastasis is the primary cause for mortality in breast cancer. We showed that breast cancer metastasis can be prevented by miR-96 or miR-182 treatment. We found that miR-96/miR-182 downregulates Palladin protein levels, thereby reducing breast cancer cell migration and invasion. A hydrogel-embedded, gold-nanoparticle-based delivery vehicle provides efficient local, selective, and sustained release of miR-96/miR-182, markedly […] Read More >
Mapping Transverse Relaxation in Preclinical MRI Scanners
UNMET NEED Accurate quantitative magnetic resonance imaging (qMRI) is gradually becoming indispensable in clinical diagnostics and research. It’s application on preclinical MRI scanners, however, is hampered by the use of strong imaging gradients, which act to increase the effects of molecular diffusion, leading to bias of the measured signals. This inherent bias makes qMRI techniques […] Read More >
Novel way to produce alcohol from waste. Producing alcohol to fight Covid -19
The increase in the world’s population as well as the development of technology and economics results among others in the increase in generation of waste. Large amounts of trash are the result of products that were consumed and discarded as Municipal Solid Waste (MSW). As biomass materials are rich in cellulose, they can be used […] Read More >
Peptide-based biomimetic hydrogels for bone regeneration
A multi-component biomimetic hydrogel scaffolds that will guide the architecture of tissue formation in bone defects. UNMET NEED Regeneration of bone defects is a major clinical challenge worldwide. The main objective is to restore and improve the function of bone tissue by scaffolds, providing a suitable environment for tissue regeneration and repair. An ideal, predictable, […] Read More >
Antibody-Based Biosensor Diagnostic tool for Pathogenic Bacteria Detection
UNMET NEED • The antibiotic resistance crisis, driven by the excessive and inappropriate use of antibiotics, is projected to result in 10 million deaths annually by 2050. Rapid and accurate diagnosis of multi-drug resistant (MDR) bacteria is essential to combat this growing global health threat. • There is a critical need for fast, reliable diagnostic […] Read More >
Rapid Detection of Drug Resistance in Patients Suffering from Invasive Fungal Infections
Global epidemics of fungal infections caused by drug resistant pathogens has beenrising sharply in recent decades including the most recently discovered Candida auris(an extensive multi-drug resistant fungal pathogen). The Echioncandin class ofantifungal drugs approved as the first-line treatment of candidaemia, invasivecandidiasis and severe infections caused by pathogenic yeast of the genus Candida,the most prevalent fungal […] Read More >
A Cost-Effective On-Site Cell-Free Biomolecules Manufacturing
ABSTRACT On-site biomolecules production is a need for many applications such as drug screening, personalized therapeutics, remote clinics, and more. CONTRALL is a silicone chip that enables cost-effective production and purification of biomolecules (proteins, Abs, etc.). The technology is especially useful for the on-site production of simple and complex biomolecules, thus surpassing the need for a […] Read More >
