245 Results were found on Technologies
Sub Category Name
Increased Enzyme Shelf-Life by Encapsulation in Peptide-Based Materials
Peptide-based nanomaterials that protect enzymes over time leading to increased shelf-life. UNMET NEED Enzymes are naturally susceptible to environmental changes resulting in their denaturation and loss of activity, thus rendering them less practical for everyday applications. The main objective is the improvement and increase in enzyme shelf-life thereby allowing their practical use in various daily […] Read More >
Therapeutic Targeting of PD-1/PD-L1 blockade by Novel Small-molecule Inhibitors
Interactions between programmed cell death ligand 1 (PD-L1) and programmed cell death protein 1 (PD-1) lead to the evasion of cancer cells from an efficient immune response. The inhibition of PD-L1/PD-1 has prevented or reversed exhausted T cells, thus enhancing antitumor T-cell responses. In fact, immune checkpoint blockade targeting the PD-1 axis has become one […] Read More >
STEREOGRADIENT POLY-(LACTIC ACID) PRODUCTION BY RING OPENING POLYMERIZATION, EMPLOYING HIGHLY ACTIVE NOVEL CATALYSTS
The Kol group at the School of Chemistry of Tel Aviv University has been developing catalysts and technologies for the ring opening polymerization of lactones, and in-particular lactide to produce PLLA-based polymers, block-copolymers and tailor-made copolymers. Recently, a new family of catalysts was developed by the Kol group. These catalysts combine several attractive properties: 1. […] Read More >
Leveraging Gene Panel Sequencing Data for Mutational Signature Analysis with Applications to Personalized Treatment
UNMET NEED Mutational signatures and their exposures are key to understanding the processes that shape cancer genomes with applications to diagnosis and treatment. Yet current signature analysis approaches are limited to relatively rich mutation data that comes from whole-genome or whole-exome sequencing. Recently, orders of magnitude sparser data sets from gene panel sequencing have become […] Read More >
High Resolution Robotic Fingers
Traditional robotic hands have a complex structure with many degrees-of-freedom, while they can be large, fragile and with high cost. In addition, they usually cannot perform gentle and precise in-hand manipulation that is required in, for example, medical procedures and assembly of small components. We propose a sophisticated mechanism that enables to augment the capabilities […] Read More >
Optimal retrieval in puzzle-based storage (PBS) systems using automated mobile robots (AMR)
Puzzle-based systems (PBS), store unit loads in very high density, without consuming space for transport aisles. In such systems, each load is stored on a moving device (conveyor module or transport vehicle), making these systems very expensive to build and maintain. We propose a new type of PBS system where loads are moved by a […] Read More >
Advanced Sensitivity in Point-of-Care Diagnostics: Electrokinetic Preconcentration Technology
As is evident from the lateral-flow-assay (LFA) that became so popular with detection of Corona virus, there is an urgent need to increase the sensitivity of detection of both point-of-care (POC) and self-testing (for example, used by individuals at home) devices. Lateral flow kits result in relatively low detection limit as only a small fraction […] Read More >
Microfluidic Flow-meter and Sensor for Drug Delivery Applications
The current structure of medical pumps does not allow real-time measurement of different parameters of drug delivery in general and low flow rates (μL/min) in particular. The current structure wherein only indirect measurements are performed (commonly pressure) makes it difficult to detect failures (e.g. air bubbles, occlusion, infiltration) in real-time on the one hand and […] Read More >
FABRICATION OF ELECTRODES WITH ULTRA-SHORT CHANNEL LENGTH
Nanofabrication represents one of the most important features of modern electronics, optoelectronics, photonics and information technologies. However, the ability to fabricate nanoscale (sub-20 nm) devices, requires the introduction of unconventional techniques for material patterning, which is cumbersome, expensive, time consuming, typically available mainly to big industrial companies or to specific research centers, hence, not reachable […] Read More >
Bio-inspired flexible piezoelectric layer showing powerful performance
The piezoelectric effect, the conversion of mechanical energy to electrical energy can serve as the basictechnology for many applications such as energy harvesting sensing and actuating. Currently, the fieldof piezoelectric materials is dominate by lead-based ceramic materials such as lead zirconate titanate(PZT). However, lead is toxic and brittle, emerging the need for alternative lead free, […] Read More >
