245 Results were found on Technologies
Sub Category Name
Overclocking LLM Reasoning- Monitoring and Controlling Thinking Path Lengths in LLMs
Large Language Models (LLMs) like ChatGPT have revolutionized AI-powered reasoning, enabling applications across diverse domains. However, their internal reasoning processes often remain opaque, leaving users in the dark about how long the model will take to arrive at an answer. UNMET NEED Currently, users interact with reasoning models without any indication of the internal progress […] Read More >
Innovative Drug Delivery: Hydrogel-Forming Microneedles with Programmed Mesophase Transitions
An innovative drug delivery system utilizing hydrogel-forming microneedles that undergo programmed mesophase transitions. This technology allows for the controlled release of drugs, enhancing the efficacy and safety of pharmaceutical treatments. The microneedles transition from solid to swollen hydrogel upon contact with biological fluids, followed by further transformation into hydrogel microparticles, which facilitates a sustained release […] Read More >
Assessing Neu5Gc Disease Risk: A Novel Diagnostic and Dietary Management Tool
Our technology identifies individuals at increased risk of developing diseases related to Neu5Gc consumption. By analyzing antibody repertoire scores and Neu5Gc intake, the method predicts disease likelihood and provides tailored dietary recommendations to reduce risk. Unmet Need Neu5Gc, a non-human sialic acid present in red meat and dairy, has been implicated in chronic inflammatory conditions […] Read More >
Bio-Inspired Liquid Compartments for Efficient Encapsulation and Controlled Release of Payloads
Tunable peptide-RNA microcompartments inspired by viral structures that have high encapsulation efficiency of small organic molecules and large macromolecules that their release is triggered by light. UNMET NEED Current drug delivery or microreactor systems are lipid-based nanoparticles (NPs) that has shown a wide range of applications as drug delivery vehicles and are used for various […] Read More >
Diagnostic Tool for Assessing Breast Cancer Aggressiveness via Neutrophil-Tumor Cell Interactions
A novel diagnostic approach based on the discovery that neutrophils physically interact with tumor cells in breast cancer, creating a unique signaling niche that enhances cancer aggressiveness. This interaction can be used to assess the aggressiveness of breast cancer, offering a new way to predict patient outcomes and guide treatment strategies. Unmet Need Current diagnostic […] Read More >
Light-Controlled Nanostructured Device for Biomolecule Separation
In the realms of proteomics, genomics, and biosensing, the analysis of complex biological samples such as blood and urine presents significant challenges. These samples contain a vast array of biomolecules, often exceeding 10,000 proteins with concentration variations spanning over 10 orders of magnitude. Traditional methods like chromatography, electrophoresis, and centrifugation are either time-consuming or lack […] Read More >
Therapeutic Targeting of CD45: A Novel Approach to Overcome Immunotherapy Resistance
Revolutionizing Cancer Immunotherapy While immune checkpoint inhibitors have transformed cancer treatment, only 50% of patients fail to respond, with resistance being a major challenge, particularly in aggressive cancers such as triple-negative breast cancer (TNBC). TNBC accounts for 15–20% of breast cancer cases and is often diagnosed at advanced stages, with current therapies offering limited efficacy. […] Read More >
P32-Specific Antibodies and CAR T Cells for Glioblastoma and P32-Expressing Tumors
This innovative immunotherapy platform leverages p32-specific antibodies to create Chimeric Antigen Receptor (CAR) T cells, specifically targeting p32—a tumor-associated antigen expressed in glioblastomas and other aggressive cancers. The approach combines tumor elimination with antiangiogenic effects, paving the way for enhanced therapeutic outcomes in solid tumors. Unmet Need Glioblastoma, a highly aggressive brain cancer, has limited […] Read More >
Energy Harvesting Module and Low Power Rectifier Circuit
RADIO frequency (RF) energy harvesting has garnered much interest in recent years as our lives have become more connected. Whether it be smart homes, industry 4.0, wearables or sport-tech; objects which were once inanimate are brought to life with electronics such as sensors, and low-power transceivers. This evolution of ‘things’ is commonly referred to as […] Read More >
Direct Seawater Splitting Technology for Pure Hydrogen Production
The quest for sustainable and renewable energy sources has intensified in recent years, driven by the urgent need to combat climate change and reduce reliance on fossil fuels. Among various approaches, direct seawater splitting presents a promising avenue for producing clean hydrogen and oxygen. This innovative technology leverages the abundant availability of seawater, eliminating the […] Read More >
