Synthetic Biology
3 Results were found on Technologies
Sub Category Name
Plant-Derived Non-CG Epigenetic Editor for Human Cells
A plant-derived epigenetic editing platform that introduces non-CG methylation into human cells. PpDNMT3 creates methylation features also found in neurons and modulates gene expression, expanding the epigenome space available for engineering and disease research. UNMET NEED DNA methylation is a central mechanism controlling gene expression and cell identity. In most human cells, methylation occurs mainly […] Read More >
Bio-Inspired Liquid Compartments for Efficient Encapsulation and Controlled Release of Payloads
Tunable peptide-RNA microcompartments inspired by viral structures that have high encapsulation efficiency of small organic molecules and large macromolecules that their release is triggered by light. UNMET NEED Current drug delivery or microreactor systems are lipid-based nanoparticles (NPs) that has shown a wide range of applications as drug delivery vehicles and are used for various […] Read More >
Enhancing Plasmid Conjugation Efficiency for Transformative Biotechnological Applications
This technology enhances plasmid-based gene transfer by utilizing a leading region enriched with anti-defense genes. It enables more efficient overcoming of bacterial immune systems, improving applications in biotechnology and microbial engineering. ABSTRACT Our groundbreaking technology dramatically improves plasmid-based gene transfer by utilizing a strategically designed leading region enriched with anti-defense genes. We revealed that the […] Read More >