198 Results were found on Technologies
Sub Category Name
Error Correction Code Transformer
Error correction code is a major part of the communication physical layer, ensuring the reliable transfer of data over noisy channels. Recently, neural decoders were shown to outperform classical decoding techniques. However, the existing neural approaches present strong overfitting due to the exponential training complexity, or a restrictive inductive bias due to reliance on Belief […] Read More >
Apparently Silent Mutations That Affect Splicing in Cancer and Other Diseases
Many mutations that cause cancer and other diseases may not be detected since they look like silent mutations that do not change the encoded proteins. One fundamental mechanism that apparently silent mutations can severely disrupt is alternative splicing. We introduce a tool that scores mutations based on models of proteomes generated using aberrant splicing predictions. […] Read More >
A Lensless Polarization Camera
Polarization imaging is a technique that creates a pixel-map of the polarization state in a scene. Although invisible to the human eye (and for most conventional cameras), polarization can assist various sensing and computer vision tasks. Existing polarization cameras acquire the additional modality using either spatial or temporal multiplexing, which increases the camera volume, weight, […] Read More >
Models for Protein Levels Optimization in Chloroplasts Based on mRNA-rRNA Folding and Interactions
Chloroplasts which have evolved from an ancestral bacterium can be the target very efficient expression of heterologous protein with huge economical potential. However, translation in chloroplasts, which have evolved from an ancestral bacterium is not well understood and currently there is no generic quantitative model related to these aspects in the chloroplast. The patent includes […] Read More >
Targeting Mitochondrial IGF-1 Receptors as Therapy for Neurodevelopmental Disorders
Neurodevelopmental brain disorders (NDDs) pose an immense burden on both the families of patients and the health and educational systems, without any effective therapies. We propose, based on our novel findings that are supported by recent clinical data, a potential gene therapy strategy that might restore the brain activity of patients to a healthy regime. […] Read More >
Deep Brain Stimulation of Thalamic Nucleus Reuniens as a New Therapeutic Tool to Prevent Neuronal and Cognitive Dysfunctions in Alzheimer’s Disease
We utilize the basic concepts of control theory and an integrative approach which spans brain-state, neural circuit, synaptic and molecular levels to boost cognitive resilience to AD pathology1,2. UNMET NEED There is no efficient, disease-modifying therapy at present for Alzheimer’s disease (AD). Even the most successful, recently FDA approved anti-amyloid drug lecanemab shows a great […] Read More >
Stabilizing Gelatin-Based Bioinks under Physiological Conditions by Incorporation of Ethylene-Glycol-Conjugated Fmoc-Ff Peptides
Peptide-based bioinks that stabilize gelatin-based 3D printed scaffolds under physiological conditions. UNMET NEED Gelatin is one of the most widely-used materials for the fabrication of 3D scaffolds. In order to fabricate stable scaffolds under physiological conditions, gelatin need to be methacrylated, allowing the crosslinking and therefore the stabilization of the hydrogel through UV treatment. However, […] Read More >
System and Method for Determining Design Parameters for Marine Infrastructure
In the 60s-70s, a remarkable advancement was reached: instruments for directional wave measurements were developed. Data processing techniques based on potential wave theory enabled for the first time the evaluation of wave directional spectra. However, the irrotational potential theory lacks essential terms of waves and ambient shearing current interactions. By constructing suitable simulations, we proved […] Read More >
LWIR / FIR / THz Detectors and Sources For High Sensitivity Remote Sensing
MIR-THz Detectors and Sources For High Sensitivity Remote Sensing The discoveries of novel materials and physical phenomena continuously drive technological advancements and their applications. So is the case for MIR-THz optoelectronics, operating roughly in the frequency range of f≈0.5-35THz. In this spectral range radiation penetrates through opaque materials without the risk of ionization, making MIR-THz […] Read More >
Highly Active and Stable Multifunctional Low-Pressure Ammonia Synthesis Catalyst
The Haber process for synthesis of ammonia is one of the most studied and important reaction of the last century. Ammonia is used mostly as a feedstock for fertilizer, but has gained considerable interest as a hydrogen carrier in a future hydrogen economy owing to its specific energy content and ease of transportation. The Haber […] Read More >
