Biological Models
71 Results were found on Technologies
Sub Category Name
Anti-Influenza A Virus Drug Discovery
Influenza A virus infection is one of the most common respiratory tract diseases in humans. It is the cause of typical seasonal flu as well as major human pandemics worldwide. According to the World Health Organization (WHO) in October 2023, around 3 to 5 million severe influenza cases were recorded, leading to 290,000 to 650,000 […] Read More >
Evaluation of Single Strand DNA Damage in Sperm Using a novel Damage Detection Technique
The Damage Detection technique is an innovative approach to assessing Single Strand DNA (ssDNA) damage by utilizing DNA repair enzymes to identify DNA adducts and single-strand breaks. Spermatozoa are characterized by high levels of DNA fragmentation, despite their condensed nuclear DNA packaging. Sublethal DNA damage, such as single strand breaks and adducts, can occur and […] Read More >
3D Printing of 3-Layered Retina and Choroid Tissue
We present a sequential fabrication of a three-layer retina-like structure. This innovative approach aims to address the challenges associated with age-related macular degeneration (AMD) and other retinal degenerative diseases by creating a bioengineered retinal implant that mimics the natural structure and function of the human retina. Unmet Need: Age-related macular degeneration is the leading cause […] Read More >
‘Super-Seaweeds’ Enriched with Nutritional and Health Compounds
The world population is growing and is expected to reach 10 billion by 2050. The increasing awareness of alternative natural products has led to a growing demand for plant-based goods. Currently, there’s an urgent need to enhance Earth’s capacity to support the expanding human population and address the depletion of natural resources. Humanity seeks a […] Read More >
Skewed Sex Ratio Technology for Livestock and Pets: Reducing Resource Wastage and Labor in Animal Breeding
Our innovative genetic engineering technology offers a transformative solution for livestock and pet industries by generating offspring with a skewed sex ratio. The technology, proven in mice, is now aimed at practical application in cattle, swine, poultry, and other farm animals, as well as pets. The Problem: Current breeding practices lead to significant waste due […] Read More >
An Improved Fast-Growing Halophilic haloarchaeon Strain
The Challenge: Halophilic archaea (HA) are ideal for biotechnological processes because they thrive in extreme conditions, requiring minimal sterility and no freshwater. However, unlike other microorganisms like fungi, algae, and bacteria, HA are underutilized in large-scale biotechnology. Currently, HA are mostly used for producing carotenoids, like bacterioruberin, and other high-value compounds. The primary species used, […] Read More >
New Formulation for Repurposing of a Drug to Treat Retinitis Pigmentosa
Heterozygous mutations in the gene encoding the RNA splicing factor pre-mRNA processing factor 31 (PRPF31) have been identified as a major cause of autosomal dominant retinitis pigmentosa (RP), a debilitating and currently incurable blinding disease. The severity and progression of RP vary significantly among patients, with some carriers remaining asymptomatic. Intriguingly, asymptomatic mutation carriers exhibit […] Read More >
Restoring Immunity Against GI Cancers
BACKGROUND GI cancers cause over 3.5 million deaths per year globally, accounting for 35% of all cancer-related deaths. Colorectal carcinoma (CRC) is the world’s second leading cause of cancer death. Current immunotherapy treatments for CRC are hamstrung by low response rate, acquired resistance, relapse and severe side effects. ImmuNovation presents a disruptive nanomodular technology utilizing […] Read More >
Discovery of a Virus That Threatens The Rainbow Trout Aquaculture
Rainbow trout (Oncorhynchus mykissis) is a North Pacific salmonid species, which, in the Western hemisphere, is the principal inland-farmed fish. In terms of production, global rainbow trout reached 600,000 tons in 2012; by 2019, it had exceeded 950,000 tons. Recently, we discovered a novel and ongoing disease in farmed rainbow trout, the hallmark of which […] Read More >
Novel Immuno-Metabolism Pathways to Combat Obesity and Insulin Resistance
Nutritional unbalance develops the obesity led to diabetes and accompanied by insulin resistance is being the epidemics of the 21st century. Inflammation of adipose tissue serves one notable pathway that is driving the development of dysfunctional metabolic state, leading to hyperglycaemia and other pathophysiology complications. Within the adipose tissue, a pivotal role in modulating interactions […] Read More >
