Diagnostics
22 Results were found on Technologies
Sub Category Name
Tailorable Sensors for Enzymatic Activity Based on Single-Walled Carbon Nanotubes with a Responsive Corona of Dendron–Polymer Hybrids
We have developed highly modular amphiphilic polymer-dendron hybrids composed of hydrophobic dendrons and hydrophilic linear polymer (e.g. polyethylene glycol (PEG)) that can be synthesized with a high degree of structural precision for suspending SWCNTs in an aqueous solution. Utilizing the susceptibility of the dendritic block of these amphiphiles toward enzymatic degradation, we demonstrated the ability […] Read More >
Point of Care Monitoring of Osteoporosis Treatment Efficacy
A small, simple, affordable, table top scanner to detect cellular changes in fat percentage in bone marrow as an early indicator of treatment efficacy. Accessible, Affordable, Sensitive, Noninvasive, at the Doctor’s clinic UNMET NEED Bone marrow adiposity in postmenopausal women increases with osteoporosis There is a negative association between bone marrow fat and the rate […] Read More >
Antibody-Based Biosensor Diagnostic tool for Pathogenic Bacteria Detection
UNMET NEED • The antibiotic resistance crisis, driven by the excessive and inappropriate use of antibiotics, is projected to result in 10 million deaths annually by 2050. Rapid and accurate diagnosis of multi-drug resistant (MDR) bacteria is essential to combat this growing global health threat. • There is a critical need for fast, reliable diagnostic […] Read More >
Molecular Harvesting with Electroporation for Tissue Profiling
Detecting tumors in unknown locations and Creating molecular maps of therapeutically relevant targets in heterogeneous tumors by molecular harvesting with electroporation. Our vision is to assist physicians to diagnose cancer more precise and help scientists and drug companies develop personalized, targeted therapies. We achieved this by providing tools for accurate spatial molecular mapping of tumors […] Read More >
Label-Free 3D Quantitative Imaging of Live Cells
A method for a real-time visualization and automatic processing for detection and classification of untouched and unstained cells during stain-free imaging flow cytometry and digital pathology using digital holographic microscopy and machine learning. UNMET NEED Most approaches dealing with the identification and characterization of specific cell types rely on using unique antigens or contrast agents. […] Read More >
An early stage screening tool for distinguishing pregnant women having an increased risk of developing preeclampsia
Preeclampsia is one of the most dangerous pregnancy complications occurs in the second or third trimester, affecting 3–8% of pregnancies; it is the leading cause of maternal and perinatal mortality and morbidity. Preeclampsia cannot reliably be predicted as no tests available in early pregnancy. OUR INNOVATION The invention is based in part on the finding […] Read More >
High Resolution Imaging of Turbid Media
Imaging through turbid (highly scattering) media such as biological tissue, milk, fog, or blood is a major challenge in scientific research, medical diagnostics, and industrial inspection. Traditional imaging techniques struggle with significant light scattering, leading to poor resolution, low contrast, and limited penetration depth. This hinders applications like high-resolution imaging inside biological tissues, quality inspection […] Read More >
A smartphone based psychiatrist-aid system to monitor and prevent recurring illnesses
Lifegraph enables early detection of disease deterioration in mental health patients, using proprietary machine-learning algorithms applied to data collected from the smartphone sensors. VISION Improving lives of patients with mental disorders and decreasing the burden of disease on patients, their families and society as a whole. NEED AND MARKET POTENTIAL Mental disorders are a leading […] Read More >
An Add-On Optical Interferometer Chamber to Phase Microscopes for Sub-Nanometer 3D and Dynamic Information
Technology An add-on optical module for microscopes allowing for single frame and dynamic capture of amplitude and phase profiles of transparent or semi-transparent biological and non-biological samples. This easyto-use interferometric device is simply positioned in the camera port of a conventional inverted microscope, enabling quantitative structural, thickness and refractive index measurements in a noncontact, label-free […] Read More >
METHODS AND KITS FOR DETERMINING PREDISPOSITION TO DEVELOP KIDNEY DISEASES
Many rare kidney disorders exhibit a monogenic, Mendelian pattern of inheritance. Population-based genetic studies have identified many genetic variants associated with an increased risk of developing common kidney diseases. Strongly associated variants have potential clinical uses as predictive markers and may advance our understanding of disease pathogenesis. These principles are elegantly illustrated by a region […] Read More >
