Research Tools
75 Results were found on Technologies
Sub Category Name
A Novel Nanoparticle that Selectively Delivers RNAi Oligonucelotides to Tumors, Preventing Side Effects to Tissues
UNMET NEEDPancreatic cancer numbers among the most aggressive cancers known today. The overwhelming majority of pancreatic cancer patients pass away within just a year of diagnosis. However, a small minority of patients may live several years with the disease. Our findings pinpoint the inverse correlation between a known oncogene (PLK1) and the expression of an […] Read More >
HYDEN (HighlY DEgeNerate primers) – A Software for designing pairs of degenerate primers for a given set of DNA sequences
Overview HYDEN (HighlY DEgeNerate primers) is a program for designing pairs of degenerate primers for a given set of DNA sequences. HYDEN works well for large input sets of genomic sequences (e.g., hundreds of sequences of length 1Kbp). HYDEN is a batch (i.e., command-line, as opposed to graphical interface) program, available for Windows XP (downloadable […] Read More >
LACTIC ACID BACTERIA FOR THE PRODUCTION OF ETHANOL FROM BIOMASS MATERIAL
The present invention, in some embodiments thereof, relates to methods and recombinant lactic acid bacteria for the production of ethanol from biomass material by a consolidated bioprocessing approach. Additional information can be provided upon request. Read More >
PNA – Self Assembled peptide nanostructures for OLED / Security applications
TechnologyWe developed nanostructures based on Peptide-Nucleic Acid (PNA) derivatives which show highly promising performance characteristics. The unique electroluminescence/photoluminescence materials can be used as emissive materials in manufacturing Organic Light-Emitting Diodes (OLED) with high emission efficiencies, tunable colors, and improved charge-transport and film-forming properties. The NeedSignificant progress has been made over the past decade in producing […] Read More >
Self Assembled Peptide Hydrogel
The Technology A breakthrough Self Assembled Peptide Hydrogel (SAPH) has been developed. SAPH is a safe, self-assembled, biocompatible, remarkably strong hydrogel with modulated stability that is suitable for various medicinal and cosmetic applications. SAPH is based on the highly efficient self-assembly of the short aromatic peptides diphenylalanine. The discovery and development of SAPH is the […] Read More >
Computational Platform for Enhancing Gene Expression for Increased Protein Yield and Viral Titer
Technology Deciphering Gene Expression Code – We perform large-scale analyses of genomic data to discern the rules behind the various aspects of gene expression encoded in the transcript. Computational Modeling of Gene Expression – We develop predictive computational models to mathematically analyze and simulate the different stages of gene expression, focusing on gene translation. Engineering […] Read More >
Molecular Classification of Inflammation and Uses for Personalized Therapy
Our work is focused on decoupling between four inflammatory molecular states: i. Disease tolerance activity. Maintenance of health in the presence of stress, injury, infection. Healing through tissue repair and renewal mechanisms. ii. Antimicrobial activity. Detects, neutralizes, and eliminates the invading pathogen (“resistance”). iii. Metabolic status. Reflects the abnormal cardiometabolic status related to hypertension, diabetes […] Read More >
Methods of Treating Diseases Associated with Polyalanine Expansion Mutations
The invention describes the inhibition of ubiquitin like modifier activating enzyme 6 (UBA6) by disease-causing polyalanine expanded mutant proteins in a variety of cell types. Polyalanine-expanded proteins can interact with UBA6 and inhibit UBA6-mediated protein degradation of downstream targets, such as the neurodevelopmental E3-ubiquitin ligase E6-AP. Ectopic administration of vectors expressing UBA6 in patient cells […] Read More >
Tomato Plants with Broad-Spectrum Pathogen Resistance
Plants rely on innate immunity to perceive and ward off microbes and pests, and are able to overcome many invading microorganisms. Even so, pathogens overcome plant defenses, posing a persistent threat to crop and food security worldwide, raising the need for agricultural products with broad, efficient resistance. The combined goal of several projects in our […] Read More >
Development of a Biological Safe Anti-Candida Agent for the Treatment of Denture Stomatitis
UNMET NEED● Denture stomatitis is a common form of oral candidiasis afflicting according to some reports up to 65% of dentures wearers.● Current treatments are based on toxic chemical agents and are non-effective.● Ani candida solution can be extended towards a broad range of other indications. Treating denture stomatitis holds clinical and patient-related significance. Firstly, […] Read More >
